The culmination of over 150 years of Japanese skincare innovation. Discover 3 visible changes in 3 days: radiance, resilience, and smoothness*. Ultimune face serum is powered by collagen-supporting peptides as well as nourishing and smoothing antioxidants to strengthen skin's protective barrier, leaving it smoother and plumper. Smooth fine lines in just 4 weeks** with Ultimune Power Infusing Serum. Now available in a refill size.